Nurse Christine Chapel
Played by: Jess Bush

Captain Christopher Pike
Played by: Anson Mount

Lieutenant Erica Ortegas
Played by: Melissa Navia

Lieutenant Jenna Mitchell
Played by: Rong Fu

Dr. Joseph M'Benga
Played by: Babs Olusanmokun

Security Chief La'an Noonien-Singh
Played by: Christina Chong

Engineer Montgomery 'Scotty' Scott
Played by: Martin Quinn

Cadet Nyota Uhura
Played by: Celia Rose Gooding

Chief Engineer Pelia
Played by: Carol Kane

Science Officer Spock
Played by: Ethan Peck

First Officer Una Chin-Riley (Number One)
Played by: Rebecca Romijin

Lieutenant George Samuel Kirk
Played by: Dan Jeannotte

Captain Marie Batel
Played by: Melanie Scrofano

Admiral Robert April
Played by: Adrian Holmes

Nurse Bo
Played by: Matia Jackett

La'an Noonien-Singh (Young)
Played by: Ava Chung

Manu Noonien-Singh
Played by: Cameron Roberts

U.S.S. Enterprise Computer Voice (2022-2025)
Played by: Alex Kapp